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The dramatic surge of health misinformation on social media platforms poses a significant threat to public health, contributing to hesitancy in vaccines, delayed medical interventions, and the adoption of untested or harmful treatments. We present a novel, hybrid AI-driven framework designed for the real-time detection of health misinformation on social media platforms while prioritizing user privacy. The framework integrates the strengths of Large Language Models (LLMs), such as DistilBERT, with domain-specific Knowledge Graphs (KGs) to enhance the detection of nuanced and contextually dependent misinformation. LLMs excel at understanding the complexities of human language, while KGs provide a structured representation of medical knowledge, allowing factual verification and identification of inconsistencies. Furthermore, the framework incorporates robust privacy-preserving mechanisms, including differential privacy and secure data pipelines, to address user privacy concerns and comply with healthcare data protection regulations. Our experimental results on a dataset of Reddit posts related to chronic health conditions demonstrate the performance of this hybrid approach compared to models that only use text or KG, highlighting the synergistic effect of combining LLMs and KGs for improved misinformation detection.more » « lessFree, publicly-accessible full text available July 8, 2026
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